Deep sedation during gastrointestinal endoscopy: Propofol-fentanyl and midazolam-fentanyl regimens

Table 1 Sedation regimens

Midazolam-fentanyl
Midazolam
Initial dose
ASA I	3-5 mg
ASA II or III	2-3 mg
Maintenance	0.5-1.0 mg every 2-3 min, up to a maximum cumulative dose of 10 mg or 0.1 mg/kg of body weight
Fentanyl
Single dose
ASA I	50 μg
ASA II or III	20-30 μg
Propofol-fentanyl
Propofol
Initial dose
ASA I	0.5 mg/kg
ASA II or III	0.25 mg/kg
Maintenance	10-20 mg bolus at 60 s intervals
Fentanyl
Single dose
ASA I	50 μg
ASA II or III	20-30 μg

ASA: American Society of Anesthesiologists.