Effect of endogenous insulin-like growth factor and stem cell factor on diabetic colonic dysmotility

Figure 1 Colonic motility dysfunction in rats with streptozotocin-induced diabetes. A: Blood glucose levels of control group and rats with streptozotocin (STZ)-induced diabetes (n = 8); B: The body weights of diabetic and age-matched control rats (n = 8); C: Colonic transit time in STZ-D and control rats 8 wk after STZ injection (n = 8); D: Circular muscle strip contractility from the representative distal colon of an STZ-D rats and control 8 wk after STZ injection and exposed to 1 μmol/L Ach. Representative images are shown; E: Quantification of maximum contractile force of a circular muscle strip stimulated by 1 μmol/L Ach (n = 8). ^aP < 0.05, ^bP < 0.01 vs the control group.