Low trypsinogen-1 expression in pediatric ulcerative colitis patients who undergo surgery

Table 1 Clinical data of the pediatric study groups at the time of diagnostic endoscopy

Patient groups	Surgery	Disease	Non-IBD
		controls	controls
No. of patients (male)	24 (11)	27 (15)	20 (10)
Age at diagnosis (yr), median (range)	13.1 (3.1-16.0)	12.1 (2.8-16.6)	13.5 (2.7-16.8)
Time from diagnosis to surgery (yr), median (range)	2.1 (0.1-7.4)	-	-
Follow-up (yr), median (range)	-	6.3 (2.8-10.7)	1.0 (0.0-4.0)
Endoscopic disease extension
Proctitis	0	1	-
Left-sided colitis	9	6	-
Pancolitis	15	20	-
No inflammation	-	-	20
Histological inflammation1
No inflammation	-	-	18
Mild	6	10	1
Moderate to severe	18	17	-
Laboratory markers, median (range)
Hb (g/L)	112 (86-135)	116 (86-140)	131.0 (93-153)
ESR (mm/h)	25 (7-61)	22 (7-63)	8 (2-23)
CRP (mg/L)	20 (< 3-92)	9 (< 5-36)	< 3 (< 3-< 5)
WBC (E9/L)	9.6 (6.7-26.3)	7.5 (4.1-15.9)	5.1 (3.0-16.3)
Alb (g/L)	34.6 (28.0-40.0)	36.2 (23.6-42.6)	42.3 (39.8-47.2)

¹For the non-inflammatory bowel disease (IBD) controls, data were missing in one case. Alb: Albumin; CRP: C-reactive protein; ESR: Erythrocyte sedimentation rate; Hb: Haemoglobin; WBC: White blood cell count.