Predominant mucosal IL-8 mRNA expression in non-cagA Thais is risk for gastric cancer

Table 3 Molecular genetic results of cyclooxygenase-2 and interleukine-8 mRNA expression in Thais n (%)

Variable	Cancer (n = 86)	Benign (n = 134)	P value
COX2 raw RQ
No expression detection	30 (34.90)	43 (53.10)	< 0.0011
Expression detection	56 (65.10)	38 (46.90)
COX2 raw RQ
mean ± SD	41.69 ± 4.90	5.37 ± 4.20	< 0.0011
COX2 log10 (N, %)
mean ± SD	1.62 ± 0.96	0.73 ± 0.62	< 0.0011
IL-8 raw RQ
No expression detection	9 (10.47)	32 (25.37)	< 0.001
Expression detection	77 (89.53)	102 (74.63)
IL-8 raw RQ
≤ 100 or undetected	33 (38.37)	105 (78.36)	< 0.001
> 100	53 (61.63)	29 (21.64)
mean ± SD	9615.64 ± 49715.00	2262.29 ± 10454.60	< 0.010
IL-8 log10
≤ 2 or undetected	32 (37.21)	105 (78.36)	< 0.001
> 2	54 (62.79)	29 (21.64)
mean ± SD	2.62 ± 1.10	1.49 ± 1.20	< 0.010

¹Some numbers are not included in the analysis due to missing laboratory data. RQ: Relative quantity; COX2: Cyclooxygenase-2; IL-8: Interleukin-8.