Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation

Figure 6 Cell signaling pathways associated with tunicamycin. A: EC109 cells were exposed to tunicamycin (TM) (5 μg/mL) for the indicated time periods, subjected to Western blotting analysis (left panel) or treated with TM at the indicated concentrations for 24 h, and subjected to Western blotting analysis (right panel); B: Western blotting analysis of cells pretreated with or without TM (5 μg/mL), followed by a single dose of 10 Gy. N: Sham-treated with TM; R: 10 Gy irradiation; GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.