Thermotherapy enhances oxaliplatin-induced cytotoxicity in human colon carcinoma cells

Figure 1 Effect of thermochemotherapy on human colon carcinoma Lovo cells. Cells were treated with oxaliplatin (12.5 μg/mL and 50 μg/mL) at different temperatures (37  °C, 39  °C, 41  °C, 43  °C or 45  °C) for 1 h and then cultured under normal conditions for 24 h. The cells were observed under inverted phase contrast microscope (Olympus, Japan) after completion of thermal therapy or thermochemotherapy.