Population-based study of DNA image cytometry as screening method for esophageal cancer

Table 2 Comparison of sensitivity, specificity, positive predictive value, negative predictive value between liquid-based cytology and DNA ploidy method based on moderate dysplasia or worse as threshold

	Threshold for positivity	Total	Se(%)	Sp(%)	PPV (%)	NPV (%)
Cytology	ASCUS+	452	75.00	91.91	50.00	97.15
	LSIL+	452	52.27	99.02	85.19	95.06
	HSIL+	452	18.18	100.00	100.00	91.89
DNA ploidy	At least 1 5cER cell	452	90.91	70.83	25.16	98.63
	At least 2 5cER cell	452	86.36	84.07	36.89	98.28
	At least 3 5cER cell	452	79.55	92.65	53.85	97.67
	At least 4 5cER cell	452	77.27	96.81	72.34	97.53
	At least 5 5cER cell	452	75.00	98.53	84.62	97.34

ASCUS: Atypical squamous cells of undetermined significance; LSIL: Low-grade squamous intraepithelial lesions; HSIL: High grade squamous intraepithelial lesion; Se: Sensitivity; Sp: Specificity; PPV: Positive predictive value; NPV: Negative predictive value.