A novel animal model for in vivo study of liver cancer metastasis

Figure 1 Macro- and microscopic images of the liver from group A mice. A: The urokinase-type plasminogen activator/severe combined immunodeficient mouse mice were transplanted with human gastric cancer cells (h-GCCs) and euthanized 56 d later, at which time the livers were isolated and photographed; B: The arrows in A point to concentrated regions of h-GCC colonies, and the sections were stained with hematoxylin and eosin (H and E). H and M in B represent h-GCC colonies and m-liver cell regions, respectively; C: The sections were stained with anti-human alpha-fetoprotein (h-AFP) antibodies; D: The square region in C is enlarged and shown.