Expression and significance of homeodomain protein Cdx2 in gastric carcinoma and precancerous lesions

Table 2 Relationship between expression of caudal-related homeobox transcription factor and clinical pathological characteristics of gastric carcinoma

Pathological parameters	n	Cdx2positive cases	Positiverate (%)	χ2	P value
Gender				0.071	0.642
Male	60	30	50
Female	25	11	44
Age (yr)				0.000	1.000
≥ 55	57	28	49.1
< 55	28	13	46.4
Lauren classification				13.544	0.001
Intestinal	43	29	67.4
Diffuse	35	9	25.7
Mixed type	7	3	42.9
Differentiation				9.991	0.001
Well and moderately differentiated	44	29	65.9
Poorly differentiated and mucinous adenocarcinoma	41	12	29.3
Depth of invasion				5.630	0.131
T1	9	7	77.8
T2	11	5	45.5
T3	25	14	56
T4	40	15	37.5
Lymph node metastasis				5.089	0.017
No	36	23	63.9
Yes	49	18	36.7
Clinical stages				5.102	0.018
I + II	19	14	73.7
III + IV	66	27	40.9

Cdx2: Caudal-related homeobox transcription factor.