Preoperative predictors of short-term survival after hepatectomy for multinodular hepatocellular carcinoma

Table 1 The baselines of clinical features at the time of diagnosis of hepatocellular carcinoma

Variable	mean/n
Age (yr)	50.16 ± 10.65 (range: 27-76)
Gender (male/female)	134:28
HBsAg-positive	156 (96.30%)
HCV-Ab positive	0
HBV-DNA
> 104/L	88 (140, 62.85%)
> 106/L	32 (140, 22.86%)
Child-Pugh score
5	148 (97.53%)
6	10 (2.47%)
TBIL (μmol/L)	15.76 ± 5.72 (range: 4.9-33)
DBIL (μmol/L)	5.51 ± 2.26 (range: 1.5-15.5)
IBIL (μmol/L)	10.28 ± 4.09 (range: 1-23)
ALB (g/L)	41.32 ± 3.59 (range: 32-53)
Prealbumin (mg/L)	217.73 ± 65.83(range:110-500)
PT > 13 s (n)	41(25.31%) (range: 10.4-17.6)
ALT > 44U/L (n)	48 (29.63%) (range: 12.9-235)
AST > 38 U/L (n)	88 (54.32%) (range: 12.8-207)
AFP > 20 μg/L	102 (62.96%) (range: 2.5-4537)
AFP > 400 μg/L	59 (36.42%)
Diabetes	14 (8.64%)
Cardiovascular hypertension	16 (9.88%)
History of smoke	50 (30.86%)
History of alcoholism	24 (14.81%)
History of other operations	20 (12.35%)
BCLC Staging
Stage A	44 (27.16%)
Stage B	118 (72.84%)
With Milan criteria	44 (27.16%)
With UCSF criteria	86 (53.09%)
TNM staging (6th, 2002 )
T2	103 (63.58%)
T3	59 (36.42%)
Total tumor size (cm)	7.58 ± 4.66 (range: 1.4-23)
The largest tumor size (cm)	5.37 ± 4.00 (range: 0.7-21)
Number of tumors
2	110
3	36
4	10
> 4	6
Serum creatinine (mmol/L)	68.65 ± 14.67 (range: 36-119)
Serum urea nitrogen (μmol/L)	5.86 ± 5.92 (range: 2.6-57)
WBC (× 109/L)	5.23 ± 1.69 (range: 1.66-11.6)
RBC (× 1012/L)	4.53 ± 0.52 (range: 3.3-6.59)
HGB (g/L)	142.8 ± 21.32 (range: 94-146)
PLT (× 109/L)	148.3 ± 75.93 (range: 31-476)
PLT < 100 × 109/L (n)	44 (27.16%)
Intraoperative transfusion	14 (8.64%)
Postoperative transfusion	6 (3.70%)
Death in 3 mo after operation	4 (2.47%)

HBsAg: Hepatitis B surface antigen; HBV: Hepatitis B virus; HCV: Hepatitis C virus; AFP: α fetoprotein; TBIL: Total bilirubin; DBIL: Direct bilirubin; IBIL: Indirect bilirubin; ALB: Albumin; PT: Prothrombin time; ALT: Alanine transaminase; AST: Aspartate aminotransferase; BCLC: Barcelona Clinic Liver Cancer; UCSF: University of California, San Francisco; WBC: White blood cell; RBC: Red blood cell; PLT: Platelet; HGB: Hematoglobulin; TNM: Tumor, nodes, metastasis.