Effects of anesthetic methods on preserving anti-tumor T-helper polarization following hepatectomy

Table 5 Plasma interferon-γ, interleukin-4, interleukin-17, interleukin-10, transforming growth factor-β1 concentrations between G + E and G groups

Variables	G + E group (pg/mL)	G group (pg/mL)	P
IFN-γ
d0	7.56 ± 0.44	6.67 ± 0.70	0.653
d2	11.17 ± 0.97	19.94 ± 1.37	0.018
d7	8.67 ± 0.74	5.76 ± 0.53	0.165
IL-4
d0	10.31 ± 1.78	10.53 ± 1.28	0.892
d2	21.11 ± 3.76	36.69 ± 6.97	0.013
d7	13.00 ± 1.88	25.50 ± 2.98	0.065
IL-17
d0	20.26 ± 5.82	18.83 ± 3.95	0.304
d2	27.26 ± 10.30	40.10 ± 10.56	0.239
d7	9.12 ± 1.67	16.66 ± 2.38	0.009
IL-10
d0	3.67 ± 0.35	3.37 ± 0.31	0.528
d2	7.17 ± 0.86	5.97 ± 0.48	0.218
d7	4.09 ± 0.29	5.65 ± 0.72	0.06
TGF-β1
d0	6565 ± 1667	5312 ± 1102	0.539
d2	15680 ± 4254	8375 ± 1395	0.12
d7	7555 ± 1555	10691 ± 2571	0.311
IFN-γ/ IL-4
d0	0.74 ± 0.10	0.65 ± 0.13	0.618
d2	0.67 ± 0.08	0.56 ± 0.05	0.309
d7	1.10 ± 0.14	0.35 ± 0.08	< 0.001

Student’s t test. G: General anesthesia; E: Epidural block; IFN-γ: Interferon-γ; IL: Interleukin; TGF: Transforming growth factor.