Efficacy and safety profile of LCR35 complete freeze-dried culture in irritable bowel syndrome: A randomized, double-blind study

Figure 2 Relative changes in irritable bowel syndrome severity score between V2 and V3, V2 and V4 in irritable bowel syndrome patients with predominance of diarrhoea. V2: Baseline; V3: At the end of the 4-wk treatment period, a more marked decrease in irritable bowel syndrome (IBS) severity score occurred with the test drug (-36.6% vs -3.1% with placebo); V4: Two weeks later, the IBS severity score was maintained below baseline with the test drug (-19.1%), whilst it slightly increased over baseline (+4.9%) with placebo.