Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 7, 2011; 17(9): 1185-1191
Published online Mar 7, 2011. doi: 10.3748/wjg.v17.i9.1185
Table 2 Diagnostic accuracy of cytomegalovirus antigenemia for detecting cytomegalovirus gastrointestinal disease
SubgroupsSensitivity (95% CI)Specificity (95% CI)PPV (95% CI)NPV (95% CI)
All patients (n = 99)65.40% (55.4-74.9)93.60% (87.3-97.7)91.90% (84.7-96.4)71.00% (60.7-79.4)
Patients with leukopenia (n = 56)68.60% (54.0-79.7)100% (93.6-100)100% (93.6-100)65.60% (52.2-78.2)
Patients without leukopenia (n = 43)58.80% (42.1-73.0)88.50% (74.9-96.1)76.90% (61.4-88.2)76.70% (61.4-88.2)
HIV-infected patients (n = 45)63.60% (48.8-78.1)100% (92.2-100)100% (92.2-100)50.00% (35.8-66.3)
Non-HIV-infected patients (n = 54)68.40% (54.5-80.5)91.40% (79.7-96.9)81.30% (68.6-90.7)84.20% (70.7-92.1)
HIV-infected patients with CD4 count < 50 (n = 22)61.90% (40.7-82.8)100% (84.6-100)100% (84.6-100)11.10% (1.12-29.2)
HIV-infected patients with CD4 count ≥ 50 (n = 23)66.70% (42.7-83.6)100% (85.2-100)100% (85.2-100)73.30% (51.6-89.8)