Viral kinetics of Enterovirus 71 in human abdomyosarcoma cells

Figure 6 Schematic view of enterovirus 71 activities in rhabdomyosarcoma cells. Within one hour of inoculation, enterovirus 71 would first attach and enter into the host cell via its specific receptors. The virus was then uncoated in the first 3 h and started to synthesize the essential viral proteins for replication. From 3 to 6 h p.i., the virus rapidly replicated its genomic RNA and initiated structure protein synthesis. Fast viral package was observed from 6 to 12 h p.i. and virion secretion increased from 6 h p.i. to the end of the observation period.