Dynamic changes and surveillance function of prion protein expression in gastric cancer drug resistance

doi:10.3748/wjg.v17.i35.3986

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Sep 21, 2011 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2011; 17(35): 3986-3993
Published online Sep 21, 2011. doi: 10.3748/wjg.v17.i35.3986

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Figure 1 Expressions of PrPc, Bcl-2 and Bax in gastric cancer cells resistant to different concentrations of adriamycin. Analysis indicated that the expressions of PrPc and Bcl-2 were markedly increased (P < 0.01), but that of Bax was significantly reduced (P < 0.01), which were in an adriamycin concentration dependent manner. Resistance index was 3.096 when the adriamycin concentration was 0.18 μg/mL. PrPc: Prion protein; RI: Resistence index.

Citation: Wang JH, Du JP, Zhang YH, Zhao XJ, Fan RY, Wang ZH, Wu ZT, Han Y. Dynamic changes and surveillance function of prion protein expression in gastric cancer drug resistance. World J Gastroenterol 2011; 17(35): 3986-3993
URL: https://www.wjgnet.com/1007-9327/full/v17/i35/3986.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i35.3986