Brief Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 21, 2011; 17(31): 3623-3629
Published online Aug 21, 2011. doi: 10.3748/wjg.v17.i31.3623
Table 1 Extrahepatic tumor burden and side effects in untreated and treated tumor-bearing rats (%)
Control group (n = 12)Monotherapy (n = 17)Combination therapy (n = 24)P value2
Tumor burden - pulmonary83.382.470.80.586
Tumor burden - abdominal91.7100.066.70.013
Ascites83.329.40.0< 0.001
Behavior141.70.025.00.019
Loss of fur16.741.266.70.015
Loss of weight (> 10% body weight)0.047.179.2< 0.001
Diarrhea16.729.462.50.015