Association between ITGA2 C807T polymorphism and gastric cancer risk

Table 2 Distributions of ITGA2 genotype in cases and controls and risk estimates n (%)

ITGA2 genotype	Cases1	Controls1	Crude OR (95% CI)	P value	Adjusted OR2 (95% CI)	P value
Overall	307	307
CC	141 (45.93)	170 (55.37)	1.00		1.00
CT	135 (43.97)	113 (36.81)	1.44 (1.03-2.01)	0.033	1.54 (1.10-2.18)	0.013
TT	31 (10.10)	24 (7.82)	1.56 (0.87-2.78)	0.133	1.62 (0.90-2.91)	0.112
CT + TT	166 (54.07)	137 (44.63)	1.46 (1.06-2.01)	0.019	1.57 (1.13-2.17)	0.007
C allele	417 (67.92)	453 (73.78)
T allele	197 (32.08)	161 (26.22)

¹Distributions of the ITGA2 genotype in cases and controls were in Hardy-Weinberg equilibrium (P = 0.988, P = 0.675, respectively);

²Adjusted for age, sex, smoking status, residence, hypertension and diabetes. OR: Odds ratio.