Effect of multidisciplinary team treatment on outcomes of patients with gastrointestinal malignancy

Table 2 Baseline characteristics of 263 patients with locally advanced rectal cancer n (%)

Baseline characteristics	NT group		Control group	P value
	(n = 101)		(n = 162)
Sex
Male	57		88	0.737
Female	44		74
Age (yr)1	55 (51-59)		55 (50-60)	0.664
Distance of tumor from anal verge
< 5 cm	35 (34.7)		37 (22.8)	0.051
5-12 cm	66 (65.3)		125 (77.2)
Surgery
APR	25		32	0.422
LAR	76		130
Preoperative serum CEA level
Normal	52 (51.5)		82 (50.6)	0.745
Abnormal	35 (34.7)		52 (32.1)
Unknown	14 (13.9)		28 (17.3)
Pretreatment staging tools
MRI	61 (60.4)		66 (40.7)	< 0.001
ERUS	28 (27.7)		34 (21.0)
CT	12 (11.9)		62 (38.3)
Pretreatment TNM stage
IIA(T3 N0)	24 (23.8)		54 (34.0)	0.278
IIB (T4 N0)	4 (4.0)		4 (2.5)
IIIA (T1-2 N1)	3 (3.0)		8 (4.9)
IIIB (T3-4 N1)	32 (31.7)		37 (22.8)
IIIC (AnyT N2)	38 (37.6)		58 (35.8)
Pathologic TNM stage
I (T1-2 N0)	35 (34.7)		12 (7.4)	< 0.01
IIA (T3 N0)	26 (25.7)		54 (33.3)
IIB (T4 N0)	1 (1.0)		0 (0)
IIIA (T1-2 N1)	6 (5.9)		7 (4.3)
IIIB (T3-4 N1)	17 (16.8)		40 (24.7)
IIIC (AnyT N2)	16 (15.8)		49 (30.2)
Histologic differentiation
High		2 (2.0)	20 (12.3)	0.013
Moderate		70 (69.3)	110 (67.9)
Poor		24 (23.8)	24 (14.8)
Mucinous and signet		5 (5.0)	8 (4.9)
Lymphovascular invasion
Present		21 (20.8)	50 (30.9)	0.074
Absent		80 (79.2)	112 (69.1)

¹Values are medians (interquartile ranges). NT: Neoadjuvant therapy; APR: Abdominal-perineal resection; LAR: Low anterior resection; MRI: Magnetic resonance imaging; ERUS: Endorectal ultrasonography; CT: computed tomography; CEA: Carcinoembryonic antigen.