MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145

Table 2 Associations between expression levels of miR-143 and miR-145 and clinicopathological features

	miR-143		miR-145
	median ± SD	P value	median ± SD	P value
Gender
Male	1.43 ± 2.99	0.805	0.82 ± 1.61	0.718
Female	1.27 ± 1.72		0.95 ± 1.32
Age (yr)
< 55	1.67 ± 3.54	0.418	1.15 ± 1.99	0.138
≥ 55	1.19 ± 1.92		0.65 ± 1.08
Diameter (cm)
< 5	1.47 ± 2.02	0.701	0.93 ± 1.31	0.497
≥ 5	1.23 ± 3.71		0.69 ± 1.89
LNM
N0	1.47 ± 3.17	0.717	0.88 ± 1.71	0.815
N1	1.25 ± 1.70		0.80 ± 1.16
Tumor stage
T1	6.31 ± 9.33	0.000b	3.33 ± 4.70	0.001b
T2	0.80 ± 1.32		0.34 ± 0.30
T3	1.25 ± 1.87		0.84 ± 1.26
Histological type
Ulcerative	1.45 ± 3.28	0.996	0.79 ± 1.76	0.955
Medullary	1.29 ± 1.72		0.90 ± 1.23
Fungating	1.32 ± 1.70		0.90 ± 1.13
Others	1.48 ± 1.18		1.27 ± 0.98
Differentiation
I	1.60 ± 2.11	0.907	0.87 ± 1.31	0.925
II	1.30 ± 3.12		0.81 ± 1.70
III	1.38 ± 1.60		1.00 ± 1.15
TNM stage
I	0.76 ± 1.00	0.971	0.94 ± 1.39	0.998
IIa	1.41 ± 2.18		0.83 ± 1.31
IIb	1.06 ± 1.47		0.95 ± 1.48
III	1.46 ± 3.60		0.87 ± 1.90

^bP < 0.01.