Original Article
Copyright ©2010 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 21, 2010; 16(47): 5965-5974
Published online Dec 21, 2010. doi: 10.3748/wjg.v16.i47.5965
Table 4 Analysis of the clinical and pathological characteristics in relation to the detection pattern of circulating tumor cells using the carcinoembryonic antigen, cytokeratin 20 and epidermal growth factor receptor multiplex assay n (%)
ParameterNo. of positive markers in each blood sample
P-value
0123
Age (yr)
< 691 (2.4)7 (17.1)26 (63.4)7 (17.1)
≥ 693 (6.4)8 (17)26 (55.3)10 (21.3)0.963
Sex
Male3 (5.4)8 (14.3)32 (57.1)13 (23.2)
Female1 (3.1)7 (21.9)20 (62.5)4 (12.5)0.294
Stage (Astler-Coller)
A + B4 (13.3)7 (23.3)17 (56.7)2 (6.7)
C0 (0)6 (22.2)17 (63)4 (14.8)
D0 (0)2 (6.5)18 (58.1)11 (35.5)< 0.001
Lymph node involvement1
≤ 34 (7.1)11 (19.6)35 (62.5)6 (10.7)
> 30 (0)4 (16)14 (56)7 (28)0.055
Tumor size (cm)2
< 32 (10.5)2 (10.5)15 (79)0 (0)
3-51 (2.5)8 (20)21 (52.5)10 (25)
> 51 (4.8)5 (23.8)11 (52.4)4 (19)0.774
Differentiation3
Well + moderate4 (6.8)10 (17)36 (61)9 (15.2)
Poor + no0 (0)4 (22.2)10 (55.6)4 (22.2)0.560
Serum CEA (ng/mL)4
< 53 (10)9 (30)12 (40)6 (20)
5-100 (0)1 (7.1)11 (78.6)2 (14.3)
> 100 (0)4 (13.3)17 (56.7)9 (30)0.029