FOXP3 expression and clinical characteristics of hepatocellular carcinoma

Table 2 Association of forkhead box protein 3 expression with pathologic grades in 140 hepatocellular carcinoma tissue arrays by immunohistochemical n (%)

Demographic or clinical characteristic	No. of tumorspecimens (n = 140)	FOXP3		P	FOXP3 immunohistochemistry intensity score				P
		Positive	Negative		0	1	2	3
Gender
Male	119	28 (24)	91 (76)	0.61932	91 (76)	20 (17)	7 (6)	1 (1)	0.48951
Female	21	6 (28)	15 (72)		15 (72)	3 (14)	3 (14)	0 (0)
Age (yr)
> 60	30	9 (30)	21 (70)	0.41032	21 (70)	4 (13)	5 (17)	0 (0)	0.15421
≤ 60	110	25 (23)	85 (77)		85 (77)	19 (17)	5 (5)	1 (1)
Differentiation grade
Well	32	11 (34)	21 (66)	0.24102	21 (66)	8 (25)	2 (6)	1 (3)	0.28871
Moderate	73	14 (19)	59 (81)		59 (81)	8 (11)	6 (8)	0 (0)
Poor	35	9 (26)	26 (74)		26 (74)	7 (20)	2 (6)	0 (0)
Tumor	140	34 (24)	106 (76)	0.04051a	106 (76)	23 (16)	10 (7)	1 (1)
Normal	14	0 (0)	14 (100)		14 (100)	0 (0)	0 (0)	0 (0)

¹Fisher's exact test;

²Pearson χ².

^aP < 0.05. FOXP3: Forkhead box protein 3.