HBx-induced reactive oxygen species activates hepatocellular carcinogenesis via dysregulation of PTEN/Akt pathway

Figure 2 Effect of hepatitis B virus X-protein on activation of the Akt pathway. A: Activation of Akt pathway was examined by Western blotting with liver tissue extracts from 6-, 11- and 13-mo-old hepatitis B virus X-protein (HBx) transgenic and wild-type mice; B: Western blotting was also performed on extracts from stable HepG2-Mock and HBx cell lines.