A predictive factor for the response to S-1 plus cisplatin in gastric cancer

doi:10.3748/wjg.v16.i36.4575

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2010; 16(36): 4575-4582
Published online Sep 28, 2010. doi: 10.3748/wjg.v16.i36.4575

Table 3 Protein expression of thymidylate synthase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase in relation to responder or non-responder on the first S-1/CDDP therapy (ng/mg protein)

	Responder (n = 6)	Non-reponder (n = 4)	t-test
TS	27.4 ± 9.4 (median 29.2)	56.9 ± 19.9 (median 53.6)	P < 0.05
DPD	170.9 ± 91.4 (median 135.7)	148.9 ± 33.5 (median 155.6)	NS
OPRT	6.1 ± 3.7 (median 6.5)	9.6 ± 9.7 (median 5.8)	NS

TS: Thymidylate synthase; DPD: Dihydropyrimidine dehydrogenase; OPRT: Orotate phosphoribosyl transferase; NS: Not significant.

Citation: Miyazaki I, Kawai T, Harada Y, Moriyasu F. A predictive factor for the response to S-1 plus cisplatin in gastric cancer. World J Gastroenterol 2010; 16(36): 4575-4582
URL: https://www.wjgnet.com/1007-9327/full/v16/i36/4575.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i36.4575