A predictive factor for the response to S-1 plus cisplatin in gastric cancer

doi:10.3748/wjg.v16.i36.4575

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 28, 2010; 16(36): 4575-4582
Published online Sep 28, 2010. doi: 10.3748/wjg.v16.i36.4575

Table 2 Protein expression of thymidylate synthase, dihydropyrimidine dehydrogenase and orotate phosphoribosyl transferase in tumour tissues and matched normal tissues (ng/mg protein)

	No. of cases	Tumour tissue	Normal tissue	Paired t-test
TS	12	42.9 ± 19.9 (median 40.5)	21.5 ± 13.7 (median 19.9)	P < 0.001
DPD	14	156.6 ± 63.3 (median 143.3)	168.1 ± 36.5 (median 170.3)	NS
OPRT	12	9.3 ± 5.8 (median 8.7)	10.1 ± 6.1 (median 8.2)	NS

TS: Thymidylate synthase; DPD: Dihydropyrimidine dehydrogenase; OPRT: Orotate phosphoribosyl transferase; NS: Not significant.

Citation: Miyazaki I, Kawai T, Harada Y, Moriyasu F. A predictive factor for the response to S-1 plus cisplatin in gastric cancer. World J Gastroenterol 2010; 16(36): 4575-4582
URL: https://www.wjgnet.com/1007-9327/full/v16/i36/4575.htm
DOI: https://dx.doi.org/10.3748/wjg.v16.i36.4575