Evaluation of cross-reactive antibody response to HVR1 in chronic hepatitis C

Figure 4 Evaluation of the cross-reactivity of anti-hypervariable region 1 antibodies in sera of chronic hepatitis C virus patients. A: Microarray patterns of 16 representative hypervariable region 1 (HVR1) proteins. The representative HVR1 proteins, negative and positive controls were printed in three replicates on the microarray; B: The value of cross-reactive responses for each sample. The number under the picture represents the value of cross-reactivity evaluated by the sum of HVR1 antigens reacted with hepatitis C virus sera.