Capecitabine with radiation is an effective adjuvant therapy in gastric cancers

Table 1 Patient characteristics n (%)

	All patients (n = 108)	XRT (n = 33)	5FU-RT (n = 52)	Chemo alone (n = 23)	P-value1 for XRT vs
					5FU-RT	Chemo alone
Age (yr)
Median	60	64	57	56	0.0032	0.032
Inter-quartile range	49.5-66.0	57.7-68.8	48.0-63.7	49.3-65.7
Gender
Male	65 (60.2)	22 (66.7)	30 (57.7)	13 (56.5)	0.5	0.6
Female	43 (39.8)	11 (33.3)	22 (42.3)	10 (43.5)
ECOG
0	6 (5.6)	1 (3.0)	3 (5.8)	2 (8.7)	1.0	0.6
1	102 (94.4)	32 (97.0)	49 (94.2)	21 (91.3)
Helicobacter pylori status
Yes	36 (53.7)	16 (66.7)	15 (50.0)	5 (38.5)	0.3	0.2
No	31 (46.3)	8 (33.3)	15 (50.0)	8 (61.5)
Surgical margins
Positive	21 (19.4)	4 (12.1)	14 (26.9)	3 (13.0)	0.2	1.0
Negative	87 (80.6)	29 (87.9)	38 (73.1)	20 (87.0)
Stage
1 or 2	38 (35.2)	12 (36.4)	14 (26.9)	12 (52.2)	0.5	0.3
3 or 4	70 (64.8)	21 (63.6)	38 (73.1)	11 (47.8)
Grade
1 or 2	31 (28.7)	12 (36.4)	12 (23.1)	7 (30.4)	0.2	0.8
3	77 (71.3)	21 (63.6)	40 (76.9)	16 (69.6)
Albumin
< 30	12 (13.3)	4 (12.9)	4 (10.0)	4 (21.1)	0.7	0.5
≥ 30	78 (86.7)	27 (87.1)	36 (90.0)	15 (78.9)
CEA
Normal	50 (90.9)	17 (89.5)	24 (92.3)	9 (90.0)	1.0	1.0
High	5 (9.1)	2 (10.5)	2 (7.7)	1 (10.0)
Hemoglobin
< 10	26 (25.7)	8 (24.2)	14 (29.2)	4 (20.0)	0.8	1.0
≥ 10	75 (74.3)	25 (75.8)	34 (70.8)	16 (80.0)

¹All P-values calculated using Fisher’s exact test unless otherwise stated;

²P-value calculated using the Mann-Whitney U test. XRT: Capecitabine + radiation; 5FU-RT: 5-fluorouracil + radiation; ECOG: Eastern Cooperative Oncology Group status; CEA: Carcinoembryonic antigen.