Correlation between pre-miR-146a C/G polymorphism and gastric cancer risk in Chinese population

Table 2 The pre-miR-146a C/G genotype distribution in cases and controls and risk estimates for variant genotypes

	Cases (%)	Controls (%)1	Crude OR (95% CI)	P value	Adjusted OR2 (95% CI)	P value
Genotype3 CC	89 (29.28)	119 (39.14)	1.00		1.00
CG	153 (50.33)	132 (43.42)	1.55 (1.08-2.22)	0.017	1.55 (1.07-2.22)	0.019
GG	62 (20.39)	53 (17.43)	1.56 (0.99-2.47)	0.056	1.62 (1.01-2.58)	0.045
GG + GC allele4	215 (70.72)	185 (60.85)	1.55 (1.11-2.18)	0.011	1.58 (1.12-2.22)	0.009
C-allele	331 (54.44)	370 (60.86)
G-allele	277 (45.56)	238 (39.14)

¹The genotype distributions complied well with Hardy-Weinberg equilibrium in cases and controls (P = 0.7993, P = 0.1223, respectively);

²Adjusted for age, sex, smoking status, hypertension, residence and diabetes;

³Pearson χ² = 6.5786, P = 0.037;

⁴Pearson χ² = 5.1232, P = 0.024.