Vitamin D receptor gene polymorphisms and hepatocellular carcinoma in alcoholic cirrhosis

Table 1 Main demographic and clinical characteristics of liver transplant recipients (n = 240) according to the presence (n = 80, 33.3%) or absence (n = 160, 66.7%) of HCC

		HCC present (n = 80)	HCC absent (n = 160)	P value
Male gender	178 (74.2)	70	108	< 0.0010
Age1 (yr)	55 (22-68)	57.2 ± 5.9	52.0 ± 8.6	< 0.0001
Body mass index1 (kg/m2)	25.2 (14.8-48.5)	26.4 ± 4.2	24.7 ± 3.3	< 0.0010
Etiology
Viral (n = 137)		50	87	NS
HBV	37 (15.4)
HCV	100 (41.7)
Alcoholic	103 (42.9)
Child-Pugh score1	8 (5-14)	7 (5-14)	8 (5-13)	< 0.0001
Child-Pugh score1 > 8 (n = 87)		22	65	< 0.0500
Diabetes mellitus	67 (27.9)	29	38	< 0.0500

The continuous variables are reported as means (standard deviation), whereas the categorical variables are reported as frequencies (%). Statistical analysis was performed using the Student’s t-test for continuous variables and the Pearson χ² test for categorical variables.

¹At transplant operation. HCC: Hepatocellular carcinoma; HBV: Hepatitis B virus; HCV: Hepatitis C virus; NS: Not significant.