Histopathology and TB-PCR kit analysis in differentiating the diagnosis of intestinal tuberculosis and Crohn’s disease

Table 2 Comparison of histopathologic parameters between ITB and CD n (%)

Histologic parameters	Cases		P value
	ITB (n = 52)	CD (n = 26)
Size of granuloma			0.000
Small (< 200 μm)	6 (11.5)	13 (50.0)
Medium (200-400 μm)	7 (13.5)	7 (26.9)
Large (> 400 μm)	39 (75.0)	5 (19.2)
Granuloma/piece > 11	24 (46.2)	9 (34.6)	0.331
Giant cells	25 (45.5)	5 (19.2)	0.015
Caseation necrosis	14 (26.9)	0 (0.0)	0.003
Confluent granuloma	24 (46.2)	2 (7.8)	0.001
Discrete granuloma	30 (57.7)	3 (11.5)	0.000
Lymphoid cuff	31 (59.6)	9 (34.6)	0.037
Ulcer with histiocytes2	17 (30.9)	3 (11.5)	0.056

¹More than one granuloma per biopsy piece;

²Ulcer with band of epithelioid histiocytes.