Aminoguanidine impedes human pancreatic tumor growth and metastasis development in nude mice

Figure 3 Histopathology and immunohistochemistry of PANC-1 xenografted mice. Formalin fixed paraffin embedded tissue sections of control mice were stained with HE. A: Metastatic lymph node (× 400); B: Xenografts (× 630). Immunohistochemistry in control and AG treated mice. Tissue sections were stained with DAB and counterstained with hematoxylin; C: Formalin fixed paraffin embedded tissue sections of control mice were stained with trichromic solution (× 400); D, G: Ki-67 (× 630); E, H: Tunel (× 400); F, I: Bax (× 630); J, M: VEGF (× 630); K, N: eNOS (× 630); L, O: CD34 in control (× 400) and AG treated (× 630) mice. Formalin fixed paraffin embedded tissue sections of control mice were stained with trichrome solution.