Association of the GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer

Table 3 Univariate and multivariate survival analysis of 122 gastric cancer patients

Covariate	n	Univariate analysis			Multivariate analysis
		P value	5-yr-SR (%)	SE (±%)	P value	HR	95% CI
pT-category		< 0.001			< 0.001
pT1	30		85.4	6.8		1
pT2	44		44.5	7.8	< 0.001	6.212	2.31-16.70
pT3	38		5.4	3.7	< 0.001	13.026	4.44-38.23
pT4	10		33.3	15.7	0.001	7.838	2.24-27.46
pN-category		< 0.001			0.549
pN0	49		61.6	7.4		1
pN1	34		47.1	8.6	0.226	0.663	0.34-1.29
pN2	14		16.9	10.9	0.986	0.993	0.43-2.27
pN3	25		8.0	5.4	0.814	0.905	0.40-2.07
T393C SNP		0.043			0.333
CC/CT	96		36.7	5.1		1
TT	26		56.9	10.4		0.712	0.36-1.42
pM-category		< 0.001			0.027
M0	99		48.1	5.2		1
M1	23		9.2	6.2		2.087	1.09-4.01
R-category		< 0.001			0.022
R0	118		42.3	4.7		1
R+	4		0	0		3.128	1.18-8.27

SNP: Single nucleotide polymorphism; 5-yr-SR: 5-yr-survival; HR: Hazard ratio.