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©2009 The WJG Press and Baishideng.
World J Gastroenterol. Dec 28, 2009; 15(48): 6061-6067
Published online Dec 28, 2009. doi: 10.3748/wjg.15.6061
Published online Dec 28, 2009. doi: 10.3748/wjg.15.6061
All | T393C genotypes | P | |||
CC | CT | TT | |||
n (%) | 122 (100) | 39 (32) | 57 (46.7) | 26 (21.3) | |
Gender | |||||
Male | 78 (63.9) | 25 (32.1) | 34 (43.6) | 19 (24.4) | |
Female | 44 (36.1) | 14 (31.8) | 23 (52.3) | 7 (15.9) | 0.274 |
WHO | |||||
Papillary/Tubular/Mucinous | 76 (62.3) | 23 (30.3) | 34 (44.7) | 19 (25) | |
Signet-ring cancer | 38 (31.1) | 12 (31.6) | 19 (50) | 7 (18.4) | |
Other | 8 (6.6) | 4 (50) | 4 (50) | 0 | 0.340 |
Differentiation | |||||
Well/Moderate (G1-G2) | 42 (34.4) | 12 (28.6) | 22 (52.4) | 8 (19) | |
Poor (G3-G4) | 80 (65.6) | 27 (33.8) | 35 (43.8) | 18 (22.5) | 0.805 |
Laurén | |||||
Intestinal | 52 (42.6) | 16 (30.8) | 25 (48.1) | 11 (21.2) | |
Diffuse | 55 (45.1) | 17 (30.9) | 29 (52.7) | 9 (16.4) | |
Mixed | 15 (12.3) | 6 (40) | 3 (20) | 6 (40) | 0.171 |
Ming | |||||
Expanding | 47 (38.5) | 14 (29.8) | 24 (51.1) | 9 (19.1) | |
Infiltrative | 75 (61.5) | 25 (33.3) | 33 (44) | 17 (22.7) | 0.620 |
pT-category | |||||
T1 | 30 (24.6) | 7 (23.3) | 13 (43.3) | 10 (33.3) | |
T2 | 44 (36.1) | 12 (27.3) | 22 (50) | 10 (22.7) | |
T3 | 38 (31.1) | 14 (36.8) | 18 (47.4) | 6 (15.8) | |
T4 | 10 (8.2) | 6 (60) | 4 (40) | 0 | 0.110 |
pN-category | |||||
N0 | 49 (40.2) | 11 (22.4) | 24 (49) | 14 (28.6) | |
N1 | 34 (27.9) | 13 (38.2) | 13 (38.2) | 8 (23.5) | |
N2 | 14 (11.5) | 6 (42.9) | 6 (42.9) | 2 (14.3) | |
N3 | 25 (20.5) | 9 (36) | 14 (56) | 2 (8) | 0.196 |
pM-category | |||||
M0 | 99 (81.1) | 30 (30.3) | 45 (45.5) | 24 (24.2) | |
M1 | 23 (18.9) | 9 (39.1) | 12 (52.2) | 2 (8.7) | 0.101 |
R-category | |||||
R0 | 118 (96.7) | 38 (32.5) | 54 (46.2) | 25 (21.4) | |
R1/R2 | 4 (3.3) | 1 (25) | 2 (50) | 1 (25) | 0.950 |
UICC stage | |||||
Ia | 26 (21.3) | 5 (19.2) | 11 (42.3) | 10 (38.5) | |
Ib | 22 (18) | 7 (31.8) | 12 (54.5) | 3 (13.6) | |
II | 18 (14.8) | 4 (22.2) | 7 (38.9) | 7 (38.9) | |
IIIa | 11 (9) | 4 (36.4) | 5 (45.5) | 2 (18.2) | |
IIIb | 4 (3.3) | 2 (50) | 2 (50) | 0 | |
IV | 41 (33.6) | 17 (41.5) | 20 (48.8) | 4 (9.8) | 0.023 |
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Citation: Alakus H, Mönig SP, Warnecke-Eberz U, Alakus G, Winde G, Drebber U, Schmitz KJ, Schmid KW, Riemann K, Siffert W, Bollschweiler E, Hölscher AH, Metzger R. Association of the
GNAS1 T393C polymorphism with tumor stage and survival in gastric cancer. World J Gastroenterol 2009; 15(48): 6061-6067 - URL: https://www.wjgnet.com/1007-9327/full/v15/i48/6061.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.6061