Effect of Lonicerae Flos extracts on reflux esophagitis with antioxidant activity

Figure 1 Changes on the gross lesion scores of Sham (A), RE (B) controls, α-tocopherol (C), LF 125 (D), 250 (E) and 500 mg/kg (F) treated rats. Sham: Normal rats had a laparotomy but not pylorus and forestomach ligation operation; RE: Rats had a pylorus and forestomach ligation operation not treated with drug; Tocopherol: Rats had a pylorus and forestomach ligation operation treated with α-tocopherol (30 mg/kg); and LF extract: Rats had a pylorus and forestomach ligation operation treated with extract of LF (respectively 125, 250 and 500 mg/kg). Values are expressed mean ± SD of five rats; ^aP < 0.05 compared to RE control; ^bP < 0.01 compared to Sham control.