Overexpression of polo-like kinase1 predicts a poor prognosis in hepatocellular carcinoma patients

Table 1 Correlations between PLK1 mRNA expression and clinicopathologic variables by Mann-Whitney U test

Factors	n	PLK1 mRNA		P
		Positive	Negative
Gender
Male	114	93	21	0.650
Female	21	18	3
Age (yr)
≤ 40	65	53	12	0.842
> 40	70	58	12
Liver cirrhosis
Yes	109	93	16	0.055
No	26	18	8
HBsAg
Positive	96	80	16	0.598
Negative	39	31	8
AFP (ng/mL)
≤ 400	51	45	6	0.156
> 400	84	66	18
Venous invasion
+ (cases)	53	48	5	0.042
- (cases)	82	63	19
Edmondson stage
I-II	56	41	15	0.022
III-IV	79	70	9
Tumor size (cm)
≤ 5. 0	36	28	8	0.417
> 5. 0	99	83	16
Tumor nodule
Single tumor nodule	77	70	7	0.002
Multiple tumor nodule	58	41	17

HBsAg: Hepatitis B surface antigen; AFP: α-fetoprotein.