Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion

doi:10.3748/wjg.15.3757

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Aug 14, 2009 (publication date) through Apr 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 14, 2009; 15(30): 3757-3766
Published online Aug 14, 2009. doi: 10.3748/wjg.15.3757

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Figure 5 The expression of MMP-2 and VEGF was analyzed by real-time PCR and Western blotting in the human pancreatic cancer cell lines. LV-STAT3siRNA-2 significantly inhibited mRNA and protein expression of MMP-2 and VEGF in SW1990 cell. A: MMP-2 mRNA expression in every group. B: VEGF mRNA expression in every group. C: P-STAT3, MMP-2 and VEGF protein expression in every group.

Citation: Yang G, Huang C, Cao J, Huang KJ, Jiang T, Qiu ZJ. Lentivirus-mediated shRNA interference targeting STAT3 inhibits human pancreatic cancer cell invasion. World J Gastroenterol 2009; 15(30): 3757-3766
URL: https://www.wjgnet.com/1007-9327/full/v15/i30/3757.htm
DOI: https://dx.doi.org/10.3748/wjg.15.3757