Characterization of focal liver lesions with SonoVue®-enhanced sonography: International multicenter-study in comparison to CT and MRI

Figure 3 44-year-old male patient with a history of rectal carcinoma. A: 2.4 cm isoechoic lesion in segment 2/3 found in B-Mode sonography; B: Contrast-enhanced sonography with SonoVue® showed a distinct rim enhancement in the peripheral zone of the lesion 13 s after injection, representing the abnormal arterial supply of the lesion; C: Early washout of the contrast enhancement in the portal phase and lack of any portal enhancement resulted in a hypo enhancement of the lesion compared to the surrounding normal liver tissue; D: In the late phase, complete lack of enhancement within the lesion (black spot) allows a clear discrimination of the lesion from the strongly enhanced normal liver tissue. The enhancement pattern is typical for a hypovascular metastasis.