Breastfeeding and genetic factors in the etiology of inflammatory bowel disease in children

Table 2 Incidence of Crohn’s disease

Annual incidence per 100000	Time period	Geographic region	Data collection	Age group studied	References
0.73	1958-1960	Nottingham, England	Retrospective	Adults	[70]
3.63	1970-1972				[70]
6.1	1971-1980	Orebro, Sweden	Retrospective	Children ≤ 16 years old	[71]
13.39 (white males)	1977-1979	Baltimore SMSA	Retrospective	All	[10]
13.54 (white females)					[10]
11.29 (non-white males)					[10]
14.08 (non-white females)					[10]
0.66	1968	Scotland	Retrospective	Children ≤ 16 years old	[72]
2.29b	1983				[72]
0.00	1920-1929	Rochester, NY	Retrospective	All	[73]
5.03	1970-1979				[73]
3.90	1980-1989				[73]
< 1.0	1962-1969	Copenhagen	Prospective	All	[74]
4.1	1979-1987				[74]
1.30	1983-1988	South Glamorgan, Wales	Retrospective	Children < 16 years old	[75]
3.11	1989-1993				[75]
21.0	1940-1943	Olmsted County, MN	Retrospective	All	[76]
27.8	1964-1973				[76]
26.9	1984-1993				[76]
14.6	1989-1994	Manitoba, Canada	Retrospective	All	[77]
21.91	1981-1983	Scotland	Retrospective	Children < 19 years old	[78]
22.91	1990-1992				[78]
5.5	1990-1994	Iceland	Prospective	All	[79]
1.2	1984-1986	Sweden	Prospective	Children < 16 years old	[80]
1.3	1993-1995				[80]
25.2	1988-1990	Northern France	Prospective	All	[81]
25.8	1991-1993				[81]
25.9	1994-1996				[81]
26.4	1997-1999				[81]
2.00	1990-1994	Southeastern Norway	Prospective	Children < 16 years old	[82]
4.56	2000-2001	Wisconsin	Prospective	Children < 18 years old	[83]

¹Age-adjusted; ²Age- and gender-adjusted; ^bP < 0.0001 compared to 1968.