Review
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jul 14, 2009; 15(26): 3217-3227
Published online Jul 14, 2009. doi: 10.3748/wjg.15.3217
Table 3 Immunohistochemical staining in the evaluation of hepatic tumors
TumorRecommended immunostaining
HCCPolyclonal CEA
Cytokeratin 8/18 pair (+/+ staining)
Cytokeratin 7/20 pair(-/- staining)
Hep Par 1, AFP
CholangiocarcinomaCytokeratin 7/19 pair (+/+ staining)
Cytokeratin 7/20 pair (+/- staining)
B-HCG, CEA, Mucin-1
Epithelioid hemangioendotheliomaCD34
CD31
Factor VIII
AngiomyolipomaHMB-45, smooth muscle actin
Metastatic carcinoma
NeuroendocrineChromagin, synaptophysin, neural enolase
PancreasCytokeratin 7/20 pair (+/+ staining)
ColorectalCytokeratin 7/20 pair( -/+ staining)
BreastCytokeratin 7/20 pair (+/- staining)
LungCytokeratin 7/20 pair (+/- staining)