Pluronic L-81 ameliorates diabetic symptoms in db/db mice through transcriptional regulation of microsomal triglyceride transfer protein

Figure 2 L-81 ameliorated diabetes. A: Food intake and (B) water intake of mice fed on a chow diet, with or without the indicated drugs (n = 3 in each group). C: Fasting plasma glucose levels of lean control mice or db/db mice treated with L-81 or rosig before and after a 21 d treatment of the indicated drugs; D: Glucose tolerance of mice treated with the indicated drugs. Mice injected with glucose had their blood glucose level monitored by Onetouch Ultra Blood Glucose Monitoring system. E: Plasma insulin level of db/db mice treated with the indicated drugs for 4 wk; F: Plasma adiponectin level of db/db mice treated with the indicated drugs for 4 wk. ^aP < 0.05 compared with untreated control.