Clinicopathological significance of B-cell-specific Moloney murine leukemia virus insertion site 1 expression in gastric carcinoma and its precancerous lesion

Table 2 Correlation between Bmi-1 expression and clinicopathological features of GC

Group	Cases (n)	Positive Bmi-1 expression rate			χ2	P
		-	+-+++	+-+++(%)
Gender					2.880	0.090
Male	116	60	56	50.0
Female	46	17	29	65.2
Age (yr)					3.658	0.056
≤ 60	82	46	36	43.9
> 60	80	31	49	61.3
Clinicopathological classification					11.190	0.001
EGC	30	6	24	80.0
AGC	132	71	61	46.2
Gross classification
EGC						0.641
I + IIc	19	3	16	84.2
III	11	3	8	72.7
AGC					6.122	0.013
BorI + BorII	25	19	6	24.0
BorIII + BorIV	107	52	55	51.4
WHO histological classification						< 0.001
PA	4	0	4	100.0
WDA	12	3	9	75.0
MDA	50	22	28	56.0		0.330a
PDA	75	42	33	44.0		0.063b
SRC	10	5	5	50.0
MA	9	4	5	55.6
UA	2	1	1	50.0
Lauren's classification					4.400	0.036
Intestinal type	75	29	46	61.3
Diffuse type	87	48	39	44.8
Lymph node metastasis					3.042	0.081
No	98	52	46	46.9
Yes	64	25	39	60.9

Fisher's exact test,

^aP = 0.330 vs PDA;

^bP = 0.063 vs PDA. EGC: Early gastric carcinoma; AGC: Advanced gastric carcinoma; PA: Papillary adenoma; WDA: Well-differentiated adenoma; MDA: Moderately differentiated adenoma; PDA: Poorly differentiated adenoma; MA: Mucinous adenoma; UA: Undifferentiated adenoma.