Antioxidant activity of chito-oligosaccharides on pancreatic islet cells in streptozotocin-induced diabetes in rats

Table 1 Effect of COS on changes of DNA damage in pancreatic β cells induced by STZ (n = 9, mean ± SD)

Group	Concentration (mg/L)	Tail length (&mgr;m)	Tail DNA (%)	Tail moment	Olive tail moment
Control		7.64 ± 6.92b	0.83 ± 1.16b	0.13 ± 0.24b	0.32 ± 0.47b
STZ		80.50 ± 31.72	29.93 ± 15.93	28.01 ± 22.34	25.73 ± 18.52
COS	10	49.90 ± 33.83a	28.41 ± 23.35	20.69 ± 21.67	17.10 ± 14.73
	100	34.67 ± 41.72b	19.77 ± 24.28	13.86 ± 20.36	11.15 ± 15.40a
	500	23.00 ± 20.79b	6.56 ± 7.57b	2.90 ± 4.12b	3.64 ± 4.54b
	1000	51.00 ± 15.44a	20.14 ± 10.51	11.48 ± 9.42	13.06 ± 6.61a

^aP < 0.05,

^bP < 0.01 vs DM group.