Protective effect of some vitamins against the toxic action of ethanol on liver regeneration induced by partial hepatectomy in rats

Table 2 Evaluation of liver regeneration parameters in each experimental group after seven days of treatment with partial hepatectomy (PH), ethanol (EtOH) and vitamins. Experimental designs are described in material and methods section

Group	Restitution liver mass’ (%)	Resected liver mass’ (g)	Final liver weight’ (g)	Liver/body ratio’ (%)	mgDNA/g liver1
Sham	None	None	9.41 ± 0.3	3.41 ± 0.2	2.1 ± 0.2
PH	83.95 ± 3.0	6.9 ± 0.3	8.27 ± 0.3	3.09 ± 0.3a	4.1 ± 0.4a
PH-EtOH	54.89 ± 2.0c	6.8 ± 0.4	5.33 ± 0.2c	1.93 ± 0.1ac	2.9 ± 0.1ac
PH-EtOH VA	62.90 ± 3.9ce	7.1 ± 0.3	6.38 ± 0.4c	2.36 ± 0.3ace	3.4 ± 0.2ace
PH-EtOH-VC	79.00 ± 2.0c	7.0 ± 0.5	7.90 ± 0.2e	2.87 ± 0.2ae	4.0 ± 0.3ae
PH-EtOH-VE	81.00 ± 3.0c	6.8 ± 0.2	7.86 ± 0.3e	3.03 ± 0.3ae	3.9 ± 0.4ae

¹Values are the mean ± SE of survivors for each experimental group (n = 8-22) as it corresponds. Vitamin A (VA); Vitamin C (VC); Vitamin E (VE).

^aP < 0.05 vs the sham group;

^cP < 0.05 vs the hepatectomized group;

^eP < 0.05 vs hepatectomized + ethanol group.