Diagnosis of Crohn’s disease in India where tuberculosis is widely prevalent

Table 2 Morphological, histological, microbiological, serological and treatment-related features n (%)

Characteristics	CD	GITB	P value
	(n = 26)	(n = 26)
Sites of involvement
Oesophagus	0 (0)	1 (3.8)	NS
Stomach	0 (0)	2 (7.7)	NS
Duodenum	1 (3.8)	2 (7.7)	NS
Jejunum	2 (7.7)	1 (3.8)	NS
Ileum	16 (61.5)	20 (76.9)	NS
Ileo-cecal valve	20 (76.9)	21 (80.7)	NS
Right colon	18 (69.2)	21 (80.7)	NS
Left colon	10 (38.4)	5 (19.2)	NS
Rectum	8 (30.7)	5 (19.2)	NS
Anal and perianal region	2 (7.7)	1 (3.8)	NS
Endoscopic and/or surgical findings
Skip lesions	6 (23.1)	2 (7.7)	NS
Deep linear/serpiginous ulcers	15 (57.7)	6 (23.1)	S
Aphthous ulcers	9 (34.6)	5 (19.2)	NS
Stricture	8 (30.7)	5 (19.2)	NS
Cobble-stone appearance	15 (57.7)	6 (23.1)	S
Pseudo polyps	9 (34.6)	5 (19.2)	NS
Neoplasm-like appearance	0 (0)	2 (7.7)	NS
Fistula	3 (11.5)	0 (0)	NS
Histological features
Granuloma	8 (30.7)	15 (57.7)	NS
Caseation	0 (0)	9 (34.6)	S
Confluence	0 (0)	6 (23.1)	S
Interpreted as IBD by pathologist	10 (38.4)	3 (11.5)	S
Interpreted as TB by pathologist	0 (0)	13 (50)	S
Interpreted as non-specific chronic inflammation by pathologist	16 (61.6)	10 (38.4)	NS
AFB smear/culture positivity	0 (0)	6 (23.1)	S
TB PCR positivity	0 (0)	17 (65.4)	S
Serological features
p-ANCA	1 (3.8)	1 (3.8)	NS
c-ANCA	1 (3.8)	0 (0)	NS
IgA ASCA	10 (38.4)	6 (23.1)	NS
IgG ASCA	10 (38.4)	11 (42.3)	NS
Treatment-related factors
Recurrence after surgery, n/total patients underwent surgery (%)	7/9 (77.7)	0/4 (0)	S
Number of patients previously treated with ATT (without any response)	9 (34.6)	-	-
Complete response to ATT	-	26 (100)	-