Acute and persisting Th2-like immune response after fractionated colorectal γ-irradiation

Figure 6 Fractionated irradiation-modified SOCS3, IL-10 and STAT3 expression. SOCS3 mRNA and protein (A), IL-10 mRNA and STAT3 protein (B) were measured in the colonic mucosa 26 wk after the end of cumulative dose of 52 Gy. Western blot analyses are showing SOCS3 and STAT3 in total protein extracts from mucosa colon. GAPDH levels are used as internal standards and relative densitometric data are analysed following normalization to the control. Dot plots of four experiments on different samples are shown. Data are expressed as the mean ± SE; ^aP < 0.05; ^bP < 0.001 vs control.