Acute and persisting Th2-like immune response after fractionated colorectal γ-irradiation

Figure 1 Effects of colorectal fractionated irradiation protocol on inflammatory mediator expression. Levels of IL-1β (A), TNFα (B), MCP-1 (C) and iNOS (D) mRNA were assessed in distal colon mucosa one day after cumulative doses of 16 Gy, 36 Gy, 52 Gy as well as 3 d after 52 Gy. The quantification of target genes was normalized to the reference gene HPRT. Data are mean ± SE, ^aP < 0.05; ^bP < 0.01; ^cP < 0.005; ^dP < 0.001 vs control.