Oxidative stress disturbs energy metabolism of mitochondria in ethanol-induced gastric mucosa injury

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Oct 14, 2008 (publication date) through Apr 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2008; 14(38): 5857-5867
Published online Oct 14, 2008. doi: 10.3748/wjg.14.5857

Table 9 Expression of mtDNA ATPase subunits 6 and 8 mRNA in ethanol-induced chronic gastric mucosa injury¹ (mean ± SD)

Group	3 wk		6 wk		9 wk
Group	mtDNA ATPase 6 mRNA	mtDNA ATPase 8 mRNA	mtDNA ATPase 6 mRNA	mtDNA ATPase 8 mRNA	mtDNA ATPase 6 mRNA	mtDNA ATPase 8 mRNA
Normal sodium	0.907 ± 0.079	0.678 ± 0.033	0.876 ± 0.045	0.671 ± 0.038	0.894 ± 0.059	0.659 ± 0.037
25% (W/W) alcohol	0.857 ± 0.062	0.655 ± 0.029	0.737 ± 0.060	0.557 ± 0.028	0.664 ± 0.039	0.512 ± 0.043
45% (W/W) alcohol	0.756 ± 0.051	0.617 ± 0.026	0.607 ± 0.039	0.474 ± 0.031	0.501 ± 0.043	0.366 ± 0.028

¹Magnitude relative to β-actin from respective specimens.

Citation: Pan JS, He SZ, Xu HZ, Zhan XJ, Yang XN, Xiao HM, Shi HX, Ren JL. Oxidative stress disturbs energy metabolism of mitochondria in ethanol-induced gastric mucosa injury. World J Gastroenterol 2008; 14(38): 5857-5867
URL: https://www.wjgnet.com/1007-9327/full/v14/i38/5857.htm
DOI: https://dx.doi.org/10.3748/wjg.14.5857