Fecal markers of inflammation used as surrogate markers for treatment outcome in relapsing inflammatory bowel disease

Table 5 PPV and NPV of a complete response after 8 wk of treatment in UC or CD calculated by using fecal marker levels above the 95th percentile as the cut-off value

Fecal marker	Patients	PPV (95% CI)	NPV (95% CI)
FC	All n = 371	30 (13-53)	100 (77-100)
FC	UC n = 27	38 (13-65)	100 (71-100)
FC	CD n = 101	14 (2-58)	100 (30-100)
MPO	All n = 371	23 (10-42)	100 (59-100)
MPO	UC n = 27	27 (10-50)	100 (48-100)
MPO	CD n = 101	12 (2-53)	100 (19-100)
EPX	All n = 371	22 (8-42)	90 (56-98)
EPX	UC n = 27	25 (8-49)	85 (42-98)
EPX	CD n = 101	14 (3-58)	100 (30-100)

¹One missing value. FC cut-off value 94.5 μg/g, MPO cut-off value 8.8 μg/g, EPX cut-off value 1.7 μg/g.