Enhanced therapeutic effects for human pancreatic cancer by application K-ras and IGF-IR antisense oligodeoxynucleotides

Figure 5 mRNA expression of K-ras gene in Patu8988 cells at 48 h post-transfection. A: RT-PCR analysis for K-ras gene in different groups. The β-actin gene was included as internal control. 1: IGF-IR ASODN group; 2: K-ras ASODN + IGF-IR ASODN; 3: K-ras ASODN group; 4: Control group; B: K-ras products quantified relative to the internal control β-actin. ^aP < 0.05, vs control. Each value represents the mean ± SD from triplicate determinations.