Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma

Table 1 Characteristics of patients with locally advanced or metastatic GBC before treatment

Characteristic	Data
Total No. of patients (evaluable for response)	25 (23)
Sex (female/male)	15/10
Median age (range)	64 (42-78)
Nevin tumor stage	n (%)
III	4 (16.0)
IV	12 (48.0)
V	9 (36.0)
ECOG performance status at baseline
0	3 (12.0)
1	17 (68.0)
2	5 (20.0)
Site of metastasis
Liver	7 (28.0)
Lung	2 (8.0)
Lymph nodes	12 (48.0)
Peritoneum	3 (12.0)
Bone	2 (8.0)
Recurrence after surgical resection	5 (20.0)
Pre-treatment requiring stent or percutaneous transhepatic drainage because of obstructive jaundice,	4 (16.0)
Pre-treatment chemotherapy	4 (16.0) 5-FU-based chemotherapy
Liver and renal functions
Total bilirubin (6-20.5 μmol/L1)
Median	18
Range	7-58
Gamma-glutamyltransferase (183.4-833.5 nkat/L1)
Median	1 033.5
Range	283.4-2 583.9
Aspartate aminotransferase/Alanine aminotransferase (0-666.8 nkat/L1)
Median	950.2
Range	383.4-1 600.3
Blood urea nitrogen (3.2-7.0 mmol/L1)
Median	6.2
Range	3.6-7.8
Serum creatinine (44-140 μmol/L1)
Median	78
Range	48-121
CA19-9 (0-39 kU/L1)
Median	496
Range	7-10 463

¹Normal level.