Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma

Table 1 Clinicopathological features of CHFR promoter methylation in GC

Variable	n	Methylated	Unmethylated	Methylated rate (%)	P value
Total	20	9	11
Age (yr)
≤ 50	6	3	3	50.00	1.000
> 50	14	6	8	42.86
Gender
Female	12	5	7	41.67	1.000
Male	8	4	4	50.00
Gastric cancer
Tumor size (cm)
< 5.0	9	5	4	55.56	0.653
≥ 5.0	11	4	7	36.36
Borrman type
I + II	10	4	6	40.00	1.000
III + IV	10	5	5	50.00
Differentiation degree
Well	6	0	6	0.00	0.014
Poorly	14	9	5	64.29
Invasive depth
Within Muscle layer	5	2	3	40.00	1.000
Penetratingmuscle layer	15	7	8	46.67
Lymph node metastasis
Positive	12	6	6	50.00	0.670
Negative	8	3	5	37.50